Biochemistry Division

Research output

Research output per year 1957 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2024

• 1591 Article
• 122 Review article
• 42 Chapter
• 42 Other contribution
• 76 More
  • 24 Comment/debate
  • 19 Letter
  • 9 Poster
  • 6 Editorial
  • 6 Short survey
  • 4 Conference contribution
  • 3 Book
  • 2 Paper
  • 2 Preprint
  • 1 Conference article

Research output per year

Research output per year

Search results

• 2024

  Amplifying Curcumin’s Antitumor Potential: A Heat-Driven Approach for Colorectal Cancer Treatment

  Kabagwira, J., Fuller, R. N., Vallejos, P. A., Sugiono, C. S., Andrianarijaona, V. M., Chism, J. B., O’leary, M. P., Molina, D. C., Langridge, W., Senthil, M. & Wall, N. R., 2024, In: OncoTargets and Therapy. 17, p. 63-78 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Designing Gold Nanoparticles for Precise Glioma Treatment: Challenges and Alternatives

  Lansangan, C., Khoobchandani, M., Jain, R., Rudensky, S., Perry, C. C. & Patil, R., Mar 2024, In: Materials. 17, 5, 1153.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Exploring the Interplay between Fatty Acids, Inflammation, and Type 2 Diabetes

  Nicholas, D. A., Mbongue, J. C., Garcia-Pérez, D., Sorensen, D., Bennit, H. F., De Leon, M. & Langridge, W. H. R., Mar 2024, In: Immuno. 4, 1, p. 91-107 17 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Neutrophil Extracellular DNA Traps in Response to Infection or Inflammation, and the Roles of Platelet Interactions

  Chen, W. A. & Boskovic, D. S., Mar 2024, In: International Journal of Molecular Sciences. 25, 5, 3025.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
• 2023

  A CTB-SARS-CoV-2-ACE-2 RBD Mucosal Vaccine Protects Against Coronavirus Infection

  Dénes, B., Fuller, R. N., Kelin, W., Levin, T. R., Gil, J., Harewood, A., Lőrincz, M., Wall, N. R., Firek, A. F. & Langridge, W. H. R., Dec 2023, In: Vaccines. 11, 12, 1865.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Asthma Care in the Elderly: Practical Guidance and Challenges for Clinical Management-A Framework of 5 “Ps”

  Khosa, J. K., Louie, S., Moreno, P. L., Abramov, D., Rogstad, D. K., Alismail, A., Matus, M. J. & Tan, L. D., 2023, In: Journal of Asthma and Allergy. 16, p. 33-43 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Development of an Animal Model for Traumatic Brain Injury Augmentation of Heterotopic Ossification in Response to Local Injury

  Kesavan, C., Gomez, G. A., Pourteymoor, S. & Mohan, S., Mar 2023, In: Biomedicines. 11, 3, 943.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• DNA condensation by cysteine containing tetra-arginine ligands as a model for ionizing radiation damage to chromatin

  Perry, C. C., Le, N. T., Allard, M. M. & Milligan, J. R., Dec 2023, In: Radiation Physics and Chemistry. 213, 111216.

  Research output: Contribution to journal › Article › peer-review

• Exosomal proteins as a source of biomarkers in colon cancer-derived peritoneal carcinomatosis – A pilot study

  Vallejos, P. A., Fuller, R. N., Kabagwira, J., Kwong, M. L., Gonda, A., McMullen, J. R. W., Le, N., Selleck, M. J., Miller, L. D., Perry, C. C., Senthil, M. & Wall, N. R., Mar 2023, In: Proteomics - Clinical Applications. 17, 2, 2100085.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Exploring the Potential of Plant-Based CTB-INS Oral Vaccines in Treating Type 1 Diabetes

  Mbongue, J. C., Vanterpool, E. & Langridge, W. H. R., Jun 2023, In: Immuno. 3, 2, p. 217-227 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• GA-OH enhances the cytotoxicity of photon and proton radiation in HPV⁺ HNSCC cells

  Chitsike, L., Bertucci, A., Vazquez, M., Lee, S., Unternaehrer, J. J. & Duerksen-Hughes, P. J., Feb 10 2023, In: Frontiers in Oncology. 13, 1070485.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Genetic Testing in the Latinx community: Impact of acculturation and provider relationships

  Ioffe, Y. J., Hong, L., Joachim-Célestin, M., Soret, C., Montgomery, S. & Unternaehrer, J. J., Feb 2023, In: Gynecologic Oncology. 169, p. 125-130 6 p.

  Research output: Contribution to journal › Article › peer-review

• Harnessing the abscopal effect for gastrointestinal malignancies in the era of immunotherapy

  Hino, C., Lee, E. W. & Yang, G. Y., 2023, In: Journal of Gastrointestinal Oncology. 14, 3, p. 1613-1625 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis

  Dhamdhere, M. R., Gowda, C. P., Singh, V., Liu, Z., Carruthers, N., Grant, C. N., Sharma, A., Dovat, S., Sundstrom, J. M., Wang, H. G. & Spiegelman, V. S., May 5 2023, In: Oncogene. 42, 19, p. 1558-1571 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Image-Guided Proton Therapy: A Comprehensive Review

  Lane, S. A., Slater, J. M. & Yang, G. Y., May 2023, In: Cancers. 15, 9, 2555.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Lack of Skeletal Effects in Mice with Targeted Disruptionof Prolyl Hydroxylase Domain 1 (Phd1) Gene Expressed in Chondrocytes

  Xing, W., Larkin, D., Pourteymoor, S., Tambunan, W., Gomez, G. A., Liu, E. K. & Mohan, S., Jan 2023, In: Life. 13, 1, 106.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Leucine Repeat Rich Kinase 1 Controls Osteoclast Activity by Managing Lysosomal Trafficking and Secretion

  Shen, S., Si, M., Zeng, C., Liu, E. K., Chen, Y., Vacher, J., Zhao, H., Mohan, S. & Xing, W., Apr 2023, In: Biology. 12, 4, 511.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Local and Systemic Effects of Porphyromonas gingivalis Infection

  Chen, W. A., Dou, Y., Fletcher, H. M. & Boskovic, D. S., Feb 2023, In: Microorganisms. 11, 2, 470.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Perianal basosquamous carcinoma treated with radiation therapy, a case report

  Kwan, S. Y., Castillo, D. R., Aka, A. A., Kandala, G., Tsai, J. Y., Zmaj, K., Reeves, M. E. & Yang, G. Y., Feb 28 2023, In: Journal of Gastrointestinal Oncology. 14, 1, p. 463-467 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Plasma Exosome Gene Signature Differentiates Colon Cancer from Healthy Controls

  Vallejos, P. A., Gonda, A., Yu, J., Sullivan, B. G., Ostowari, A., Kwong, M. L., Choi, A., Selleck, M. J., Kabagwira, J., Fuller, R. N., Gironda, D. J., Levine, E. A., Hughes, C. C. W., Wall, N. R., Miller, L. D. & Senthil, M., Jun 2023, In: Annals of Surgical Oncology. 30, 6, p. 3833-3844 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Reprogramming of human peripheral blood mononuclear cells into induced mesenchymal stromal cells using non-integrating vectors

  Chen, W., Wang, C., Yang, Z. X., Zhang, F., Wen, W., Schaniel, C., Mi, X., Bock, M., Zhang, X. B., Qiu, H. & Wang, C., Dec 2023, In: Communications Biology. 6, 1, 393.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Sequential application of small molecule therapy enhances chondrogenesis and angiogenesis in murine segmental defect bone repair

  Rundle, C. H., Gomez, G. A., Pourteymoor, S. & Mohan, S., Jul 2023, In: Journal of Orthopaedic Research. 41, 7, p. 1471-1481 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Sialic acids Neu5Ac and KDN in adipose tissue samples from individuals following habitual vegetarian or non-vegetarian dietary patterns

  Guerrero-Flores, G. N., Pacheco, F. J., Boskovic, D. S., Pacheco, S. O. S., Zhang, G., Fraser, G. E. & Miles, F. L., Dec 2023, In: Scientific Reports. 13, 1, 12593.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Signaling pathways and regulation of gene expression in hematopoietic cells

  Bogush, D., Schramm, J., Ding, Y., He, B., Singh, C., Sharma, A., Tukaramrao, D. B., Iyer, S., Desai, D., Nalesnik, G., Hengst, J., Bhalodia, R., Gowda, C. & Dovat, S., May 2023, In: Advances in Biological Regulation. 88, 100942.

  Research output: Contribution to journal › Review article › peer-review

• Synergistic effect of HDAC inhibitor Chidamide with Cladribine on cell cycle arrest and apoptosis by targeting HDAC2/c-Myc/RCC1 axis in acute myeloid leukemia

  Gu, S., Hou, Y., Dovat, K., Dovat, S., Song, C. & Ge, Z., Dec 2023, In: Experimental Hematology and Oncology. 12, 1, 23.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeting Tumor Microenvironment Akt Signaling Represents a Potential Therapeutic Strategy for Aggressive Thyroid Cancer

  Mirshahidi, S., Yuan, I. J., Simental, A., Lee, S. C., Peterson, N. R., Andrade Filho, P. A., Murry, T., Duerksen-Hughes, P. & Yuan, X., Mar 2023, In: International Journal of Molecular Sciences. 24, 6, 5471.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• TSLP as a Potential Therapy in the Treatment of CRLF2 B Cell Acute Lymphoblastic Leukemia

  Alkashgari, H. R., Ruiz-Jimenez, C., Stoian, C., Coats, J. S., Baez, I., Chirshev, E., Martinez, S. R., Dovat, S., Francis-Boyle, O. L., Casiano, C. A. & Payne, K. J., Jan 2023, In: International Journal of Molecular Sciences. 24, 1, 474.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Vitamin D Deficiency (VDD) and Benefits of Supplementation in Veterans with IBS-D

  Kesavan, C., Das, A., Goyal, P., Jackson, C. S., Strong, D. D. & Strong, R. M., Sep 2023, In: Diagnostics. 13, 17, 2807.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• WNT16 Regulation of the Articular Chondrocyte Phenotype in Mice

  Mohan, S., Pourteymoor, S. & Kesavan, C., Apr 2023, In: Life. 13, 4, 878.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2022

  Aminoflavone upregulates putative tumor suppressor miR-125b-2-3p to inhibit luminal A breast cancer stem cell-like properties

  Mavingire, N., Campbell, P., Liu, T., Wooten, J., Khan, S., Chen, X., Matthews, J., Wang, C. & Brantley, E., Jun 1 2022, In: Precision Clinical Medicine. 5, 2, pbac008.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A phase II trial of gemcitabine and erlotinib followed by ChemoProton therapy plus capecitabine and oxaliplatin for locally advanced pancreatic cancer

  Sanghvi, S. M., Coffman, A. R., Hsueh, C. T., Kang, J., Park, A., Solomon, N. L., Garberoglio, C. A., Reeves, M. E., Slater, J. D. & Yang, G. Y., Aug 2022, In: Journal of Gastrointestinal Oncology. 13, 4, p. 1989-1996 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Calcium released by osteoclastic resorption stimulates autocrine/paracrine activities in local osteogenic cells to promote coupled bone formation

  Ahmed, A. S. I., Sheng, M. H. C., Lau, K. H. W., Wilson, S. M., Wongwarawat, D., Tang, X., Ghahramanpouri, M., Nehme, A., Xu, Y., Abdipour, A., Zhang, X. B., Wasnik, S. & Baylink, D. J., May 2022, In: American Journal of Physiology - Cell Physiology. 322, 5, p. C977-C990

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinician-Scientist Faculty Mentoring Program (FAME) – A New Inclusive Training Model at Penn State Increases Scholarly Productivity and Extramural Grant Funding

  Dovat, S., Gowda, C., Mailman, R. B., Parent, L. J. & Huang, X., 2022, In: Advances in Medical Education and Practice. 13, p. 1039-1050 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Contrasting effects of Ksr2, an obesity gene, on trabecular bone volume and bone marrow adiposity

  Gomez, G. A., Rundle, C. H., Xing, W., Kesavan, C., Pourteymoor, S., Lewis, R. E., Powell, D. R. & Mohan, S., 2022, In: eLife. 11, e82810.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Convalescent Plasma for COVID-19: A Single Center Prospective Experience with Serial Antibody Measurements and Review of the Literature

  Whang, S. N., Shah, V. D., Pu, L., Sheth, P., Lucas, G. N., Lee, J., Lee, M., Lacy, C., Duerksen-Hughes, P. J., Filippov, V., Lee, D. J. H., Veltman, J., Maken, K., Reeves, M. E., Stevens, W. T., Herrmann, P., Cao, H. & Lau, E., Sep 2022, In: Pathogens. 11, 9, 958.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Correction: Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia (Biomarker Research, (2022), 10, 1, (16), 10.1186/s40364-022-00367-3)

  Xu, Y., Hino, C., Baylink, D. J., Xiao, J., Reeves, M. E., Zhong, J. F., Mirshahidi, S. & Cao, H., Dec 2022, In: Biomarker Research. 10, 1, 33.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• CRISPR–Cas9 gene editing induced complex on-target outcomes in human cells

  Wen, W. & Zhang, X. B., Jun 2022, In: Experimental Hematology. 110, p. 13-19 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Differences in pathways contributing to thyroid hormone effects on postnatal cartilage calcification versus secondary ossification center development

  Gomez, G. A., Aghajanian, P., Pourteymoor, S., Larkin, D. & Mohan, S., Jan 2022, In: eLife. 11, e76730.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• FBP1-Altered Carbohydrate Metabolism Reduces Leukemic Viability through Activating P53 and Modulating the Mitochondrial Quality Control System In Vitro

  Xu, Y., Tran, L., Tang, J., Nguyen, V., Sewell, E., Xiao, J., Hino, C., Wasnik, S., Francis-Boyle, O. L., Zhang, K. K., Xie, L., Zhong, J. F., Baylink, D. J., Chen, C. S., Reeves, M. E. & Cao, H., Oct 2022, In: International Journal of Molecular Sciences. 23, 19, 11387.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Gold Nanostar Characterization by Nanoparticle Tracking Analysis

  Le, N. T., Boskovic, T. J. M., Allard, M. M., Nick, K. E., Kwon, S. R. & Perry, C. C., Dec 13 2022, In: ACS Omega. 7, 49, p. 44677-44688 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Heavy metals in the blueband hermit crab, Pagurus samuelis (Stimpson, 1857) (Decapoda: Anomura: Paguridae), from two Southern California habitats

  Dos Santos, T. S. D., Boskovic, D. S., Shih, W. & Dunbar, S. G., Mar 1 2022, In: Journal of Crustacean Biology. 42, 1, ruac015.

  Research output: Contribution to journal › Article › peer-review

• High efficacy of Azacitidine plus HAG in acute myeloid leukemia: an open-label, single-arm, multi-center, phase 2 study

  Li, J., Han, Q., Huang, Y., Wei, Y., Zi, J., Zhao, L., Cai, Z., Lu, X., Xiao, R., Zhang, Y., Yang, X., Xu, H., Sun, N., Zhuang, W., Wu, Z., Xia, Y., Xu, Y., He, B., Zhu, W., Min, F., & 15 othersChen, Y., Ding, B., Shi, P., Xie, J., Tang, H., Liu, Z., Li, B., Sun, Y., Qiu, H., Duan, L., Dovat, E., Song, C., SzeKely, L., Dovat, S. & Ge, Z., Oct 2022, In: Blood Cancer Journal. 12, 10, 145.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Improved and Flexible HDR Editing by Targeting Introns in iPSCs

  Fu, J., Fu, Y. W., Zhao, J. J., Yang, Z. X., Li, S. A., Li, G. H., Quan, Z. J., Zhang, F., Zhang, J. P., Zhang, X. B. & Sun, C. K., Jun 2022, In: Stem Cell Reviews and Reports. 18, 5, p. 1822-1833 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Lipopolysaccharide-Induced Immunological Tolerance in Monocyte-Derived Dendritic Cells

  Mbongue, J. C., Vanterpool, E., Firek, A. & Langridge, W. H. R., Sep 2022, In: Immuno. 2, 3, p. 482-500 19 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Mice with Targeted Knockout of Tetraspanin 3 Exhibit Reduced Trabecular Bone Mass Caused by Decreased Osteoblast Functions

  Xing, W., Pourteymoor, S., Kesavan, C., Gomez, G. A. & Mohan, S., Mar 1 2022, In: Cells. 11, 6, 977.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Modulation of Immune Reaction in Hydrodynamic Gene Therapy for Hemophilia A

  Zhao, M., Sun, Y. D., Yin, M., Zhao, J. J., Li, S. A., Li, G., Zhang, F., Xu, J., Meng, F. Y., Zhang, B., Sun, X. Y., Zhang, J. P., Cheng, T. & Zhang, X. B., Apr 2022, In: Human Gene Therapy. 33, 7-8, p. 404-420 17 p.

  Research output: Contribution to journal › Article › peer-review

• Molecular Classes and Growth Hormone Treatment Effects on Behavior and Emotion in Patients with Prader–Willi Syndrome

  Mahmoud, R., Swanson, H. D., Butler, M. G., Flodman, P., Gold, J. A., Miller, J. L., Roof, E., Osann, K., Dykens, E., Driscoll, D. J. & Kimonis, V., May 1 2022, In: Journal of Clinical Medicine. 11, 9, 2572.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Monocyte Chemotactic Proteins Mediate the Effects of Hyperglycemia in Chondrocytes: In Vitro Studies

  Quincey, A., Mohan, S. & Edderkaoui, B., Jun 2022, In: Life. 12, 6, 836.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Novel Casein Kinase II (CK2) inhibitor BMS-135 shows significant in vivo anti-leukemia effect

  Gowda, C., Purandare, A., Mercer, K., Duke, K. & Dovat, S., Oct 2022, In: European Journal of Cancer. 174, p. S29

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine

  Wang, H., Chan, K. Y. Y., Cheng, C. K., Ng, M. H. L., Lee, P. Y., Cheng, F. W. T., Lam, G. K. S., Chow, T. W., Ha, S. Y., Chiang, A. K. S., Leung, W. H., Leung, A. Y. H., Wang, C. C., Zhang, T., Zhang, X. B., So, C. C., Yuen, Y. P., Sun, Q., Zhang, C., Xu, Y., & 15 othersCheung, J. T. K., Ng, W. H., Tang, P. M. K., Kang, W., To, K. F., Lee, W. Y. W., Wong, R. S. M., Poon, E. N. Y., Zhao, Q., Huang, J., Chen, C., Yuen, P. M. P., Li, C. K., Leung, A. W. K. & Leung, K. T., Nov 1 2022, In: Blood cancer discovery. 3, 6, p. 516-535 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access