Leucine Repeat Rich Kinase 1 Controls Osteoclast Activity by Managing Lysosomal Trafficking and Secretion

Sandi Shen, Mingjue Si, Canjun Zeng, Elaine K. Liu, Yian Chen, Jean Vacher, Haibo Zhao, Subburaman Mohan, Weirong Xing

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number511
JournalBiology
Volume12
Issue number4
DOIs
StatePublished - Apr 2023

ASJC Scopus Subject Areas

  • General Biochemistry,Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Agricultural and Biological Sciences

Keywords

  • Lrrk1
  • OSTM1
  • acidification
  • bone formation
  • bone mineral density
  • bone resorption
  • cathepsin K
  • knockout
  • lysosome
  • osteoclast
  • osteopetrosis

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