Cancer, Developmental and Regenerative Biology

Research output

Research output per year 2000 2012 2017 2018 2019 2020 2023 2024

• 38 Article
• 3 Review article
• 1 Chapter
• 1 Comment/debate
• 1 More
  • 1 Editorial

Research output per year

Research output per year

Search results

• 2024

  A Stem-like Patient-Derived Ovarian Cancer Model of Platinum Resistance Reveals Dissociation of Stemness and Resistance

  Suzuki, T., Conant, A., Jung, Y., Bax, R., Antonissen, A., Chen, W., Yu, G., Ioffe, Y. J., Wang, C. & Unternaehrer, J. J., Apr 2024, In: International Journal of Molecular Sciences. 25, 7, 3843.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2023

  GA-OH enhances the cytotoxicity of photon and proton radiation in HPV⁺ HNSCC cells

  Chitsike, L., Bertucci, A., Vazquez, M., Lee, S., Unternaehrer, J. J. & Duerksen-Hughes, P. J., Feb 10 2023, In: Frontiers in Oncology. 13, 1070485.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Genetic Testing in the Latinx community: Impact of acculturation and provider relationships

  Ioffe, Y. J., Hong, L., Joachim-Célestin, M., Soret, C., Montgomery, S. & Unternaehrer, J. J., Feb 2023, In: Gynecologic Oncology. 169, p. 125-130 6 p.

  Research output: Contribution to journal › Article › peer-review

• Glucocorticoid Receptor Regulates and Interacts with LEDGF/p75 to Promote Docetaxel Resistance in Prostate Cancer Cells

  Sanchez-Hernandez, E. S., Ochoa, P. T., Suzuki, T., Ortiz-Hernandez, G. L., Unternaehrer, J. J., Alkashgari, H. R., Diaz Osterman, C. J., Martinez, S. R., Chen, Z., Kremsky, I., Wang, C. & Casiano, C. A., Aug 2023, In: Cells. 12, 16, 2046.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Racial and Ethnic Disparities in Gynecologic Carcinosarcoma: A Single-Institution Experience

  Mercado, K. E., Badiner, N. M., Wang, C., Denham, L., Unternaehrer, J. J., Hong, L. J. & Ioffe, Y. J., Oct 2023, In: Cancers. 15, 19, 4690.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Role of epithelial-mesenchymal transition factor SNAI1 and its targets in ovarian cancer aggressiveness

  Suzuki, T., Conant, A., Curow, C., Alexander, A., Ioffe, Y. & Unternaehrer, J. J., 2023, In: Journal of Cancer Metastasis and Treatment. 9, 25.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
• 2022

  TOP1 inhibition induces bifurcated JNK/MYC signaling that dictates cancer cell sensitivity

  Liu, Q., Chung, S., Murata, M. M., Han, B., Gao, B., Zhang, M., Lee, T. Y., Chirshev, E., Unternaehrer, J., Tanaka, H., Giuliano, A. E., Cui, Y. & Cui, X., 2022, In: International Journal of Biological Sciences. 18, 10, p. 4203-4218 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2021

  Let-7i reduces aggressive phenotype and induces BRCAness in ovarian cancer cells

  Chirshev, E., Suzuki, T., Wang, H., Nguyen, A., Hojo, N., Sanderman, L., Mirshahidi, S., Ioffe, Y. J. & Unternaehrer, J. J., Sep 2021, In: Cancers. 13, 18, 4617.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The epithelial–mesenchymal transcription factor snai1 represses transcription of the tumor suppressor miRNA let-7 in cancer

  Wang, H., Chirshev, E., Hojo, N., Suzuki, T., Bertucci, A., Pierce, M., Perry, C., Wang, R., Zink, J., Glackin, C. A., Ioffe, Y. J. & Unternaehrer, J. J., Mar 2 2021, In: Cancers. 13, 6, p. 1-18 18 p., 1469.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2020

  A Single Tertiary Site Review of Gynecologic Carcinosarcomas: Rising Incidence of A Lethal Disease

  Wang, C., Hong, L., Denham, L., Unternaehrer, J., Ioffe, Y. & Unternaehrer, J. J., Mar 1 2020, In: Gynecologic Oncology. 156

  Research output: Contribution to journal › Article › peer-review

• Epithelial/mesenchymal heterogeneity of high-grade serous ovarian carcinoma samples correlates with miRNA let-7 levels and predicts tumor growth and metastasis

  Chirshev, E., Hojo, N., Bertucci, A., Sanderman, L., Nguyen, A., Wang, H., Suzuki, T., Brito, E., Martinez, S. R., Castañón, C., Mirshahidi, S., Vazquez, M. E., Wat, P., Oberg, K. C., Ioffe, Y. J. & Unternaehrer, J. J., Nov 1 2020, In: Molecular Oncology. 14, 11, p. 2796-2813 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Germline BRCA Mutation Rates in Latina Women Presenting for Gynecologic Oncology Care

  Hong, L., Gonzalez, R., Unternaehrer, J. & Ioffe, Y., Jun 1 2020, In: Gynecologic and Obstetric Investigation. 85, 3, p. 214-221 8 p.

  Research output: Contribution to journal › Article › peer-review

• Rate of osseous metastases as identified by PET/CT in endometrial cancer: serous histology is a significant risk factor

  Hong, L., Cristiano, L., Cristiano, B., Unternaehrer, J., Ioffe, Y. & Unternaehrer, J. J., Mar 1 2020, In: Gynecologic Oncology. 156

  Research output: Contribution to journal › Article › peer-review
• 2019

  Epithelial-mesenchymal Transition and Cancer Stem Cells: At the Crossroads of Differentiation and Dedifferentiation

  Wang, H. & Unternaehrer, J. J., Jan 2019, In: Developmental Dynamics. 248, 1, p. 10-20 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Let - 7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer

  Chirshev, E., Oberg, K. C., Ioffe, Y. J. & Unternaehrer, J. J., Aug 28 2019, In: Clinical and translational medicine. 8

  Research output: Contribution to journal › Article › peer-review

• Putative tumor suppressor cytoglobin promotes aryl hydrocarbon receptor ligand–mediated triple negative breast cancer cell death

  Rowland, L. K., Campbell, P. S., Mavingire, N., Wooten, J. V., McLean, L., Zylstra, D., Thorne, G., Daly, D., Boyle, K., Whang, S., Unternaehrer, J. & Brantley, E. J., Apr 2019, In: Journal of Cellular Biochemistry. 120, 4, p. 6004-6014 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2018

  Abstract 2024: Hyaluronic acid conjugated nanoparticle delivery of siTWIST reduces tumor burden and enhances chemosensitivity in ovarian cancer

  Glackin, C. A., Shahin, S. A., Simargi, S., Wang, R., Contreras, A., Parra, L., Qu, L., Wen, W., Dellinger, T., Unternaehrer, J., Tamanoi, F., Zink, J. & Unternaehrer, J. J., Jul 1 2018, In: Cancer Research. 78

  Research output: Contribution to journal › Article › peer-review

• Hyaluronic acid conjugated nanoparticle delivery of siRNA against TWIST reduces tumor burden and enhances sensitivity to cisplatin in ovarian cancer

  Shahin, S. A., Wang, R., Simargi, S. I., Contreras, A., Parra Echavarria, L., Qu, L., Wen, W., Dellinger, T., Unternaehrer, J., Tamanoi, F., Zink, J. I. & Glackin, C. A., Jun 2018, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 4, p. 1381-1394 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance

  Ross, C. K. C. D., Martinez, S. R., Woods-Burnham, L., Durán, A. M., Roy, S., Basu, A., Ramirez, J. A., Ortiz-Hernández, G. L., Ríos-Colón, L., Chirshev, E., Sanchez-Hernandez, E. S., Soto, U., Greco, C., Boucheix, C., Chen, X., Unternaehrer, J., Wang, C. & Casiano, C. A., Jul 1 2018, In: Oncotarget. 9, 54, p. 30363-30384 22 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Snail knockdown reverses stemness and inhibits tumour growth in ovarian cancer

  Hojo, N., Huisken, A. L., Wang, H., Chirshev, E., Kim, N. S., Nguyen, S. M., Campos, H., Glackin, C. A., Ioffe, Y. J. & Unternaehrer, J. J., Dec 1 2018, In: Scientific Reports. 8, 1, 8704.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2017

  Bony metastases as identified by PET/CT in early stage and advanced endometrial cancer

  Cristiano, L., Hong, L., Gonzalez, R., Abu-Tabikh, S., Unternaehrer, J., Ioffe, Y. & Unternaehrer, J. J., Jan 10 2017, In: Gynecologic Oncology. 147

  Research output: Contribution to journal › Article › peer-review

• Germline BRCA mutation rate in Southern California Latina women

  Hong, L., Gonzalez, R., Abu-Tabikh, S., Cristiano, L., Nguyen, S., Unternaehrer, J., Ioffe, Y. & Unternaehrer, J. J., Oct 1 2017, In: Gynecologic Oncology. 147

  Research output: Contribution to journal › Article › peer-review

• Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β

  Nicholas, D. A., Zhang, K., Hung, C., Glasgow, S., Aruni, A. W., Unternaehrer, J., Payne, K. J., Langridge, W. H. R. & De Leon, M., May 2017, In: PLoS ONE. 12, 5, e0176793.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Regulation of Stemness in Carcinoma Cells

  Hao, J., Unternaehrer, J., Cui, X., Cheng, N. & Oji, Y., 2017, In: Stem Cells International. 2017, 7681769.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
• 2016

  Chimeric vaccine stimulation of human dendritic cell indoleamine 2, 3-dioxygenase occurs via the non-canonical NF-kB pathway

  Kim, N. S., Mbongue, J. C., Nicholas, D. A., Esebanmen, G. E., Unternaehrer, J. J., Firek, A. F. & Langridge, W. H. R., Feb 2016, In: PLoS ONE. 11, 2, e0147509.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2014

  A nontranscriptional role for Oct4 in the regulation of mitotic entry

  Zhaoa, R., Deibler, R. W., Leroud, P. H., Ballabeni, A., Heffner, G. C., Cahan, P., Unternaehrer, J. J., Kirschner, M. W. & Daley, G. Q., Nov 4 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 44, p. 15768-15773 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming

  Unternaehrer, J. J., Zhao, R., Kim, K., Cesana, M., Powers, J. T., Ratanasirintrawoot, S., Onder, T., Shibue, T., Weinberg, R. A. & Daley, G. Q., 2014, In: Stem Cell Reports. 3, 5, p. 691-698 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2013

  Influence of threonine metabolism on S-adenosylmethionine and histone methylation

  Shyh-Chang, N., Locasale, J. W., Lyssiotis, C. A., Zheng, Y., Teo, R. Y., Ratanasirintrawoot, S., Zhang, J., Onder, T., Unternaehrer, J. J., Zhu, H., Asara, J. M., Daley, G. Q. & Cantley, L. C., Jan 11 2013, In: Science. 339, 6116, p. 222-226 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2012

  Chromatin-modifying enzymes as modulators of reprogramming

  Onder, T. T., Kara, N., Cherry, A., Sinha, A. U., Zhu, N., Bernt, K. M., Cahan, P., Marcarci, B. O., Unternaehrer, J., Gupta, P. B., Lander, E. S., Armstrong, S. A. & Daley, G. Q., Mar 29 2012, In: Nature. 483, 7391, p. 598-602 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Erratum: Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells (Nature Biotechnology (2011) 29 (1117-1119))

  Kim, K., Zhao, R., Doi, A., Ng, K., Unternaehrer, J., Cahan, P., Hongguang, H., Loh, Y. H., Aryee, M. J., Lensch, M. W., Li, H., Collins, J. J., Feinberg, A. P. & Daley, G. Q., Jan 2012, In: Nature Biotechnology. 30, 1, p. 112 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

  Xu, C., Fan, Z. P., Müller, P., Fogley, R., DiBiase, A., Trompouki, E., Unternaehrer, J., Xiong, F., Torregroza, I., Evans, T., Megason, S. G., Daley, G. Q., Schier, A. F., Young, R. A. & Zon, L. I., Mar 13 2012, In: Developmental Cell. 22, 3, p. 625-638 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2011

  Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

  Kim, K., Zhao, R., Doi, A., Ng, K., Unternaehrer, J., Cahan, P., Hongguang, H., Loh, Y. H., Aryee, M. J., Lensch, M. W., Li, H., Collins, J. J., Feinberg, A. P. & Daley, G. Q., Dec 2011, In: Nature Biotechnology. 29, 12, p. 1117-1119 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Induced pluripotent stem cells for modeling human diseases

  Unternaehrer, J. J. & Daley, G. Q., Jul 4 2011, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 366, 1575, p. 2274-2285 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
• 2008

  Spinophilin participates in information transfer at immunological synapses

  Bloom, O., Unternaehrer, J. J., Jiang, A., Shin, J. S., Delamarre, L., Allen, P. & Mellman, I., Apr 21 2008, In: Journal of Cell Biology. 181, 2, p. 203-211 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2007

  Disruption of E-Cadherin-Mediated Adhesion Induces a Functionally Distinct Pathway of Dendritic Cell Maturation

  Jiang, A., Bloom, O., Ono, S., Cui, W., Unternaehrer, J., Jiang, S., Whitney, J. A., Connolly, J., Banchereau, J. & Mellman, I., Oct 26 2007, In: Immunity. 27, 4, p. 610-624 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2006

  Nurine myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging

  Tesar, B. M., Walker, W. E., Unternaehrer, J., Joshi, N. S., Chandele, A., Haynes, L., Kaech, S. & Goldstein, D. R., Dec 2006, In: Aging Cell. 5, 6, p. 473-486 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Presentation of self-antigens on MHC class II molecules during dendritic cell maturation

  Zwickey, H. L., Unternaehrer, J. J. & Mellman, I., Jan 2006, In: International Immunology. 18, 1, p. 199-209 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2005

  Chapter 2 – MHC Class II

  Chow, A. Y. & Unternaehrer, J. J., Jan 1 2005, In: Default journal.

  Research output: Contribution to journal › Article › peer-review

• Targeting antigen to CD19 on B cells efficiently activates T cells

  Yan, J., Wolff, M. J., Unternaehrer, J., Mellman, I. & Mamula, M. J., Jul 2005, In: International Immunology. 17, 7, p. 869-877 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2004

  MHC Class II

  Chow, A. Y., Unternaehrer, J. J. & Mellman, I., Dec 30 2004, Measuring Immunity: Basic Science and Clinical Practice. Elsevier, p. 12-22 11 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells

  Meyer Zum Bueschenfelde, C. O., Unternaehrer, J., Mellman, I. & Bottomly, K., Nov 15 2004, In: Journal of Immunology. 173, 10, p. 6119-6124 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2001

  Distinct patterns of membrane microdomain partitioning in Th1 and Th2 cells

  Balamuth, F., Leitenberg, D., Unternaehrer, J., Mellman, I. & Bottomly, K., 2001, In: Immunity. 15, 5, p. 729-738 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2000

  Large-scale culture and selective maturation of human Langerhans cells from granulocyte colony-stimulating factor-mobilized CD34⁺ progenitors

  Gatti, E., Velleca, M. A., Biedermann, B. C., Ma, W., Unternaehrer, J., Ebersold, M. W., Medzhitov, R., Pober, J. S. & Mellman, I., Apr 1 2000, In: Journal of Immunology. 164, 7, p. 3600-3607 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Transport of peptide-MHC class II complexes in developing dendritic cells

  Turley, S. J., Inaba, K., Garrett, W. S., Ebersold, M., Unternaehrer, J., Steinman, R. M. & Mellman, I., Apr 21 2000, In: Science. 288, 5465, p. 522-527 6 p.

  Research output: Contribution to journal › Article › peer-review