Therapeutic challenges in the management of gout in the elderly

Harinder Singh, Karina D. Torralba

Research output: Contribution to journalShort surveypeer-review

Abstract

Gout is the most common inflammatory arthritis In the elderly population. Management in the elderly requires special consideration. Physiologic changes associated with aging and co-morbidities make the elderly prone to adverse effects of drugs otherwise successfully used in younger counterparts. Use of colchicine, non-steroidal anti-inflammatory drugs, and urate-lowering therapies may be restricted in those with limited renal reserve. Corticosteroids are safe alternatives for short-term use in acute gout. Elderly patients need laboratory monitoring for side effects more frequently than usual. Non-pharmacologic measures such as dietary modifications, regular exercise, and Ice therapy should be considered vital adjunctive treatments. A brief review of future therapies is also discussed.

Original languageEnglish
Pages (from-to)13-20
Number of pages8
JournalGeriatrics
Volume63
Issue number7
StatePublished - Jul 2008

ASJC Scopus Subject Areas

  • Geriatrics and Gerontology

Keywords

  • Elderly
  • Gout
  • Hyperuricemia

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