TY - JOUR
T1 - The diagnosis and treatment of osteoporosis
T2 - Future prospects
AU - Baylink, David J.
AU - Strong, Donna D.
AU - Mohan, Subburaman
N1 - Osteoporosis is a common disease that affects millions of patients throughout the world. We anticipate that both the diagnosis and the treatment of th...
PY - 1999/3/1
Y1 - 1999/3/1
N2 - Osteoporosis is a common disease that affects millions of patients throughout the world. We anticipate that both the diagnosis and the treatment of this disease will be revolutionized by the integration of genomics and informatics. It is predicted that a genetic algorithm will be developed to identify at-risk patients before they develop osteoporosis, so that preventive measure can be instituted. The sequencing of the human genome will lead to revolutionary advances in at least three areas of osteoporosis therapy: small molecule therapy, protein therapy and gene therapy. One area of focus for future therapeutics in osteoporosis will be on osteogenic agents, which should have a high likelihood of success because the skeleton has the innate capacity to regenerate itself.
AB - Osteoporosis is a common disease that affects millions of patients throughout the world. We anticipate that both the diagnosis and the treatment of this disease will be revolutionized by the integration of genomics and informatics. It is predicted that a genetic algorithm will be developed to identify at-risk patients before they develop osteoporosis, so that preventive measure can be instituted. The sequencing of the human genome will lead to revolutionary advances in at least three areas of osteoporosis therapy: small molecule therapy, protein therapy and gene therapy. One area of focus for future therapeutics in osteoporosis will be on osteogenic agents, which should have a high likelihood of success because the skeleton has the innate capacity to regenerate itself.
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U2 - 10.1016/S1357-4310(98)01426-9
DO - 10.1016/S1357-4310(98)01426-9
M3 - Review article
C2 - 10203737
SN - 1357-4310
VL - 5
SP - 133
EP - 140
JO - Molecular Medicine Today
JF - Molecular Medicine Today
IS - 3
ER -