Systemic Treatments for Allergic Contact Dermatitis

Calvin T. Sung; Maria A. McGowan; Brian C. Machler; Sharon E. Jacob

doi:10.1097/DER.0000000000000435

Systemic Treatments for Allergic Contact Dermatitis

Calvin T. Sung, Maria A. McGowan, Brian C. Machler, Sharon E. Jacob

Dermatology

Research output: Contribution to journal › Review article › peer-review

Abstract

Allergic contact dermatitis is a common disease within the family of delayed-type hypersensitivity reactions. In more severe cases of allergic contact dermatitis, topical steroids may prove insufficient, and systemic therapeutic agents are often used. Even when systemic therapies such as cyclosporine lead to improvement, withdrawal of these agents is challenging and can lead to undesirable morbidities. Currently, there are no systemic treatments indicated for the treatment of widespread recalcitrant contact dermatitis. This review discusses the targets of in-use off-label systemic medications and potential therapeutics in the pipeline.

Original language	English
Pages (from-to)	46-53
Number of pages	8
Journal	Dermatitis
Volume	30
Issue number	1
DOIs	https://doi.org/10.1097/DER.0000000000000435
State	Published - Jan 1 2019

ASJC Scopus Subject Areas

Immunology and Allergy
Dermatology

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abstract = "Allergic contact dermatitis is a common disease within the family of delayed-type hypersensitivity reactions. In more severe cases of allergic contact dermatitis, topical steroids may prove insufficient, and systemic therapeutic agents are often used. Even when systemic therapies such as cyclosporine lead to improvement, withdrawal of these agents is challenging and can lead to undesirable morbidities. Currently, there are no systemic treatments indicated for the treatment of widespread recalcitrant contact dermatitis. This review discusses the targets of in-use off-label systemic medications and potential therapeutics in the pipeline.",

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Systemic Treatments for Allergic Contact Dermatitis

Abstract

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