Systematic review of in vitro studies evaluating tooth bleaching efficacy

So Ran Kwon, Elisa Cortez, Min Wang, Mohit Jagwani, Udochukwu Oyoyo, Yiming Li

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose: To review and assess the literature on in vitro studies evaluating tooth bleaching efficacy considering the use of a negative control, type of tooth substrate, storage medium, color evaluation methods, and evaluation time points. Methods: The following databases were searched: PubMed (MEDLINE), Web of Science. Search used Medical Subject Headings (MeSH) in PubMed in addition to free text. The following limits were applied: English, articles published between January 1989 and October 2017. Additional free text key terms included: in vitro, tooth bleaching, placebo, negative control, overall CIELAB color change (ΔE∗ab), change in shade guide units (ASGU), tooth color stabilization, evaluation time points, bovine teeth, and staining. Search was repeated in Web of Science but no additional articles were identified. A total of 11 studies were included for qualitative and quantitative analysis. Results: The meta-analysis of nine included studies that reported ΔE∗ab values, revealed that the NC statistically exceeded the perceptibility threshold (PT) of 1.2 (P< 0.05). The estimate was 2.872 with lower and upper bounds of 1.955 and 3.790, respectively.

Original languageEnglish
Pages (from-to)17-24
Number of pages8
JournalAmerican Journal of Dentistry
Volume33
Issue number1
StatePublished - Feb 2020

ASJC Scopus Subject Areas

  • General Medicine

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