Pathophysiology of Subarachnoid Hemorrhage, Early Brain Injury, and Delayed Cerebral Ischemia

C. Reis; W. M. Ho; O. Akyol; S. Chen; R. Applegate; John H. Zhang

doi:10.1016/B978-0-12-803058-5.00025-4

Pathophysiology of Subarachnoid Hemorrhage, Early Brain Injury, and Delayed Cerebral Ischemia

C. Reis, W. M. Ho, O. Akyol, S. Chen, R. Applegate, John H. Zhang

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Subarachnoid hemorrhage (SAH) has high morbidity and mortality rates because there is no sufficient treatment so far. The major topics in SAH research focus on early brain injury and delayed cerebral ischemia causing neurological deficits and bad outcome. Therefore understanding of the underlying mechanisms of SAH is mandatory for the development of successful SAH treatment strategies. In this chapter, we summarize the pathophysiology of subarachnoid hemorrhage, including early brain injury and delayed cerebral ischemia.

Original language	English
Title of host publication	Primer on Cerebrovascular Diseases
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	125-130
Number of pages	6
ISBN (Print)	9780128030585
DOIs	https://doi.org/10.1016/B978-0-12-803058-5.00025-4
State	Published - Mar 7 2017

ASJC Scopus Subject Areas

General Neuroscience

Keywords

Delayed cerebral ischemia
Early brain injury
Intracranial aneurysm
Pathophysiology
Subarachnoid hemorrhage
Vasospasm

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AU - Chen, S.

AU - Applegate, R.

AU - Zhang, John H.

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AB - Subarachnoid hemorrhage (SAH) has high morbidity and mortality rates because there is no sufficient treatment so far. The major topics in SAH research focus on early brain injury and delayed cerebral ischemia causing neurological deficits and bad outcome. Therefore understanding of the underlying mechanisms of SAH is mandatory for the development of successful SAH treatment strategies. In this chapter, we summarize the pathophysiology of subarachnoid hemorrhage, including early brain injury and delayed cerebral ischemia.

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KW - Early brain injury

KW - Intracranial aneurysm

KW - Pathophysiology

KW - Subarachnoid hemorrhage

KW - Vasospasm

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BT - Primer on Cerebrovascular Diseases

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ER -

Pathophysiology of Subarachnoid Hemorrhage, Early Brain Injury, and Delayed Cerebral Ischemia

Abstract

ASJC Scopus Subject Areas

Keywords

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