TY - JOUR
T1 - Patent Foramen Ovale Closure for Hypoxemia
AU - Tobis, Jonathan M.
AU - Narasimha, Deepika
AU - Abudayyeh, Islam
N1 - Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2017/10
Y1 - 2017/10
N2 - A patent foramen ovale (PFO) is a common anatomic finding in 20% of the normal population. Significant hypoxemia can occur in circumstances in which hemodynamic or anatomic changes predispose to increased right-to-left intra-atrial shunting. The subsequent hypoxemia produces substantial dyspnea that may affect the patient's quality of life, independent of underlying pulmonary disease. Profound hypoxemia caused by right-to-left shunt across the interatrial septum usually responds to percutaneous PFO closure. An important impediment to successful treatment is the lack of awareness of the potential role of a PFO in this condition.
AB - A patent foramen ovale (PFO) is a common anatomic finding in 20% of the normal population. Significant hypoxemia can occur in circumstances in which hemodynamic or anatomic changes predispose to increased right-to-left intra-atrial shunting. The subsequent hypoxemia produces substantial dyspnea that may affect the patient's quality of life, independent of underlying pulmonary disease. Profound hypoxemia caused by right-to-left shunt across the interatrial septum usually responds to percutaneous PFO closure. An important impediment to successful treatment is the lack of awareness of the potential role of a PFO in this condition.
KW - COPD
KW - Hypoxemia
KW - Patent foramen ovale
KW - Platypnea-orthodeoxia
KW - Right-to-left shunting
UR - http://www.scopus.com/inward/record.url?scp=85023757863&partnerID=8YFLogxK
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U2 - 10.1016/j.iccl.2017.05.003
DO - 10.1016/j.iccl.2017.05.003
M3 - Review article
C2 - 28886845
SN - 2211-7458
VL - 6
SP - 547
EP - 554
JO - Interventional Cardiology Clinics
JF - Interventional Cardiology Clinics
IS - 4
ER -