Overall safety of peroxides

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Current tooth whiteners contain peroxides as active ingredients, which release hydrogen peroxide (H2O2) in the process of application. The primary source of safety concerns with the peroxide-based tooth whiteners is the capability of H2O2to produce oxidative free radicals or reactive oxygen species (ROS), which have been associated with various pathological consequences including carcinogenesis and degenerative diseases. This chapter will review and discuss toxicology of H2O2, its presence in the human body, and its potential systemic effects, genotoxicity, and carcinogenicity on the basis of evidence available in the literature.

Original languageEnglish
Title of host publicationTooth Whitening
Subtitle of host publicationAn Evidence-Based Perspective
PublisherSpringer International Publishing
Pages35-44
Number of pages10
ISBN (Electronic)9783319388496
ISBN (Print)9783319388472
DOIs
StatePublished - Jan 1 2016

ASJC Scopus Subject Areas

  • General Dentistry

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