Modification of Kynurenine Pathway via Inhibition of Kynurenine Hydroxylase Attenuates Surgical Brain Injury

George Zakhary; Prativa Sherchan; Qian Li; Jiping Tang; John H. Zhang

Modification of Kynurenine Pathway via Inhibition of Kynurenine Hydroxylase Attenuates Surgical Brain Injury

George Zakhary, Prativa Sherchan, Qian Li, Jiping Tang, John H. Zhang

Physiology Division

Research output: Contribution to conference › Poster

Original language	American English
State	Published - Jan 1 2018
Event	MU-COM RESEARCH DAY - Duration: Jan 1 2018 → …

Conference

Conference	MU-COM RESEARCH DAY
Period	1/1/18 → …

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Pharmacology

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@conference{7cebcef161c84eb49a88eacd38a6e026,

title = "Modification of Kynurenine Pathway via Inhibition of Kynurenine Hydroxylase Attenuates Surgical Brain Injury",

author = "George Zakhary and Prativa Sherchan and Qian Li and Jiping Tang and Zhang, {John H.}",

note = "Neurosurgical procedures result in surgically-induced brain injury (SBI) that causes postoperative complications including brain edema and neuronal apoptosis in the surrounding brain tissue. SBI leads to the release of cytokines that indirectly cause the stimulation of kynurenine 3-monooxygenase (KMO) and the release of neurotoxic quinolinic acid (QUIN).; MU-COM RESEARCH DAY ; Conference date: 01-01-2018",

year = "2018",

month = jan,

day = "1",

language = "American English",

}

TY - CONF

T1 - Modification of Kynurenine Pathway via Inhibition of Kynurenine Hydroxylase Attenuates Surgical Brain Injury

AU - Zakhary, George

AU - Sherchan, Prativa

AU - Li, Qian

AU - Tang, Jiping

AU - Zhang, John H.

N1 - Neurosurgical procedures result in surgically-induced brain injury (SBI) that causes postoperative complications including brain edema and neuronal apoptosis in the surrounding brain tissue. SBI leads to the release of cytokines that indirectly cause the stimulation of kynurenine 3-monooxygenase (KMO) and the release of neurotoxic quinolinic acid (QUIN).

PY - 2018/1/1

Y1 - 2018/1/1

UR - https://mushare.marian.edu/mucom_rd/65/

M3 - Poster

T2 - MU-COM RESEARCH DAY

Y2 - 1 January 2018

ER -

Modification of Kynurenine Pathway via Inhibition of Kynurenine Hydroxylase Attenuates Surgical Brain Injury

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