Delayed recanalization in acute ischemic stroke patients: Late is better than never?

Jinwei Pang, John H. Zhang, Yong Jiang

Research output: Contribution to journalComment/debatepeer-review

Abstract

Successful recanalization of the occluded vessel as early as possible has been widely accepted as the key principle of acute ischemic stroke (AIS) treatment. Unfortunately, for many years, the vast majority of AIS patients were prevented from receiving effective recanalization therapy because of a narrow therapeutic window. Recently, a series of inspiring clinical trials have indicated that more patients may benefit from delayed recanalization during an expanded therapeutic window, even up to 24 h after symptom onset.

Original languageEnglish
Pages (from-to)2536-2538
Number of pages3
JournalJournal of Cerebral Blood Flow and Metabolism
Volume39
Issue number12
DOIs
StatePublished - Dec 1 2019

ASJC Scopus Subject Areas

  • Neurology
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Keywords

  • Acute ischemic stroke
  • clinical trials
  • delayed recanalization
  • penumbra
  • therapeutic window

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