Computed Tomography to Determine the Cause of Primary Aldosteronism

M. D. Gross; J. E. Freitas; R. J. Grekin; W. H. Beierwaltes; Douglas C. Smith; M. C.Theodore Mackett; Phiroze E. Billmoria; Morris Schambelan; Albert A. Moss; Edward G. Biglieri; Eric A. White; Melvin Korobkin; Charles R. Rost

doi:10.1056/NEJM198104233041720

Computed Tomography to Determine the Cause of Primary Aldosteronism

M. D. Gross, J. E. Freitas, R. J. Grekin, W. H. Beierwaltes, Douglas C. Smith, M. C.Theodore Mackett, Phiroze E. Billmoria, Morris Schambelan, Albert A. Moss, Edward G. Biglieri, Eric A. White, Melvin Korobkin, Charles R. Rost

General Angiography Division

Research output: Contribution to journal › Letter › peer-review

Abstract

To the Editor: As stated in the article by White and his co-workers in the December 25 issue,¹ after a biochemical diagnosis of primary aldosteronism has been made adrenal cortical scintigraphy can be used to confirm the presence and location of aldosterone-producing adrenal adenomas. Although [¹³¹I]6β-iodomethylnorcholesterol (NP-59) remains under application as an investigational new drug, it has proved efficacy. It will remain an investigational agent because of economic considerations, but it is readily available. Initial and subsequent studies have demonstrated a high degree of sensitivity (90 per cent) and accuracy (90 per cent)² when scintiscans are performed with strict.

Original language	English
Pages (from-to)	1046-1047
Number of pages	2
Journal	New England Journal of Medicine
Volume	304
Issue number	17
DOIs	https://doi.org/10.1056/NEJM198104233041720
State	Published - Apr 23 1981

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General Medicine

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Gross, M. D., Freitas, J. E., Grekin, R. J., Beierwaltes, W. H., Smith, D. C., Mackett, M. C. T., Billmoria, P. E., Schambelan, M., Moss, A. A., Biglieri, E. G., White, E. A., Korobkin, M., & Rost, C. R. (1981). Computed Tomography to Determine the Cause of Primary Aldosteronism. New England Journal of Medicine, 304(17), 1046-1047. https://doi.org/10.1056/NEJM198104233041720

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title = "Computed Tomography to Determine the Cause of Primary Aldosteronism",

abstract = "To the Editor: As stated in the article by White and his co-workers in the December 25 issue,1 after a biochemical diagnosis of primary aldosteronism has been made adrenal cortical scintigraphy can be used to confirm the presence and location of aldosterone-producing adrenal adenomas. Although [131I]6β-iodomethylnorcholesterol (NP-59) remains under application as an investigational new drug, it has proved efficacy. It will remain an investigational agent because of economic considerations, but it is readily available. Initial and subsequent studies have demonstrated a high degree of sensitivity (90 per cent) and accuracy (90 per cent)2 when scintiscans are performed with strict.",

author = "Gross, {M. D.} and Freitas, {J. E.} and Grekin, {R. J.} and Beierwaltes, {W. H.} and Smith, {Douglas C.} and Mackett, {M. C.Theodore} and Billmoria, {Phiroze E.} and Morris Schambelan and Moss, {Albert A.} and Biglieri, {Edward G.} and White, {Eric A.} and Melvin Korobkin and Rost, {Charles R.}",

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T1 - Computed Tomography to Determine the Cause of Primary Aldosteronism

AU - Gross, M. D.

AU - Freitas, J. E.

AU - Grekin, R. J.

AU - Beierwaltes, W. H.

AU - Smith, Douglas C.

AU - Mackett, M. C.Theodore

AU - Billmoria, Phiroze E.

AU - Schambelan, Morris

AU - Moss, Albert A.

AU - Biglieri, Edward G.

AU - White, Eric A.

AU - Korobkin, Melvin

AU - Rost, Charles R.

PY - 1981/4/23

Y1 - 1981/4/23

N2 - To the Editor: As stated in the article by White and his co-workers in the December 25 issue,1 after a biochemical diagnosis of primary aldosteronism has been made adrenal cortical scintigraphy can be used to confirm the presence and location of aldosterone-producing adrenal adenomas. Although [131I]6β-iodomethylnorcholesterol (NP-59) remains under application as an investigational new drug, it has proved efficacy. It will remain an investigational agent because of economic considerations, but it is readily available. Initial and subsequent studies have demonstrated a high degree of sensitivity (90 per cent) and accuracy (90 per cent)2 when scintiscans are performed with strict.

AB - To the Editor: As stated in the article by White and his co-workers in the December 25 issue,1 after a biochemical diagnosis of primary aldosteronism has been made adrenal cortical scintigraphy can be used to confirm the presence and location of aldosterone-producing adrenal adenomas. Although [131I]6β-iodomethylnorcholesterol (NP-59) remains under application as an investigational new drug, it has proved efficacy. It will remain an investigational agent because of economic considerations, but it is readily available. Initial and subsequent studies have demonstrated a high degree of sensitivity (90 per cent) and accuracy (90 per cent)2 when scintiscans are performed with strict.

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JO - New England Journal of Medicine

JF - New England Journal of Medicine

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ER -

Computed Tomography to Determine the Cause of Primary Aldosteronism

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