Research output

Research output per year 2008 2018 2019 2020 2021 2022 2024

• 78 Article
• 18 Review article
• 6 Editorial
• 5 Comment/debate
• 1 More
  • 1 Chapter

Research output per year

Research output per year

Search results

• 2024

  Adjuvant proton beam therapy in patients with grade 2 meningiomas

  Wilson, T. A., Kang, J. I., Huang, L., Vacaru, A., Martins, K. N. & Boling, W. W., 2024, In: Surgical Neurology International. 15, 62.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Delayed recanalization reduced neuronal apoptosis and neurological deficits by enhancing liver-derived trefoil factor 3-mediated neuroprotection via LINGO2/EGFR/Src signaling pathway after middle cerebral artery occlusion in rats

  Li, D., Lian, L., Huang, L., Gamdzyk, M., Huang, Y., Doycheva, D., Li, G., Yu, S., Guo, Y., Kang, R., Tang, H., Tang, J., Kong, L. & Zhang, J. H., Jan 2024, In: Experimental Neurology. 371, 114607.

  Research output: Contribution to journal › Article › peer-review

• Mitochondrial ferritin upregulation reduced oxidative stress and blood-brain-barrier disruption by maintaining cellular iron homeostasis in a neonatal rat model of germinal matrix hemorrhage

  Yuan, Y., He, Q., Yang, X., Flores, J. J., Huang, L., Luo, X., Zhang, X., Zhang, Z., Li, R., Gu, L., Dong, S., Zhu, S., Yi, K., Han, M., Wu, L., Zhou, Y., Zhang, J. H., Xie, Z. & Tang, J., Apr 2024, In: Experimental Neurology. 374, 114703.

  Research output: Contribution to journal › Article › peer-review

• UDP-Glucose/P2Y14 Receptor Signaling Exacerbates Neuronal Apoptosis after Subarachnoid Hemorrhage in Rats

  Kanamaru, H., Zhu, S., Dong, S., Takemoto, Y., Huang, L., Sherchan, P., Suzuki, H., Tang, J. & Zhang, J. H., May 1 2024, In: Stroke. 55, 5, p. 1381-1392 12 p.

  Research output: Contribution to journal › Article › peer-review
• 2023

  Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH

  Chen, X., He, X., Xu, F., Xu, N., Sharifi, N. H., Zhang, P., Flores, J. J., Wu, L., He, Q., Kanamaru, H., Zhu, S., Dong, S., Han, M., Yuan, Y., Huang, L., Miao, L., Zhang, J. H., Zhou, Y. & Tang, J., Sep 1 2023, In: Stroke. 54, 9, p. 2420-2433 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Intra-hematoma Rosiglitazone infusion therapy attenuates blood-brain barrier disruption after intracerebral hemorrhage in rabbits

  Ren, S., Wang, L., Wu, G., Huang, L. & Tang, Z., Jun 2023, In: Brain Hemorrhages. 4, 2, p. 47-52 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Recombinant Slit2 suppresses neuroinflammation and Cdc42-mediated brain infiltration of peripheral immune cells via Robo1–srGAP1 pathway in a rat model of germinal matrix hemorrhage

  Li, Q., Huang, L., Ding, Y., Sherchan, P., Peng, W. & Zhang, J. H., Dec 2023, In: Journal of Neuroinflammation. 20, 1, 249.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Role of Estrogen-Related Receptor γ and PGC-1α/SIRT3 Pathway in Early Brain Injury After Subarachnoid Hemorrhage

  Guo, Y., Hu, Y., Huang, Y., Huang, L., Kanamaru, H., Takemoto, Y., Li, H., Li, D., Gu, J. & Zhang, J. H., Apr 2023, In: Neurotherapeutics. 20, 3, p. 822-837 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Three Days Delayed Recanalization Improved Neurological Function in pMCAO Rats by Increasing M2 Microglia—Possible Involvement of the IL-4R/STAT6/PPARγ Pathway

  Kang, R., Gamdzyk, M., Luo, Y., Tang, H., Huang, L., Lenahan, C., Doycheva, D., Li, D., Tang, J., Tan, S. & Zhang, J. H., Apr 2023, In: Translational Stroke Research. 14, 2, p. 250-262 13 p.

  Research output: Contribution to journal › Article › peer-review
• 2022

  Inhibition of caspase-1-mediated inflammasome activation reduced blood coagulation in cerebrospinal fluid after subarachnoid haemorrhage

  Fang, Y., Wang, X., Lu, J., Shi, H., Huang, L., Shao, A., Zhang, A., Liu, Y., Ren, R., Lenahan, C., Tang, J., Zhang, J., Zhang, J. H. & Chen, S., Feb 2022, In: eBioMedicine. 76, 103843.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Inhibition of Prostaglandin E2 Receptor EP3 Attenuates Oxidative Stress and Neuronal Apoptosis Partially by Modulating p38MAPK/FOXO3/Mul1/Mfn2 Pathway after Subarachnoid Hemorrhage in Rats

  Liu, Y., Liu, R., Huang, L., Zuo, G., Dai, J., Gao, L., Shi, H., Fang, Y., Lu, Q., Okada, T., Wang, Z., Hu, X., Lenahan, C., Tang, J., Xiao, J. & Zhang, J. H., 2022, In: Oxidative Medicine and Cellular Longevity. 2022, 7727616.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Meeting report – Online STIPE trial kick-off meeting

  Chen, D., Tang, Y., Yang, J., Huang, L. & Tang, Z., Jun 2022, In: Brain Hemorrhages. 3, 2, p. 103-104 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Met-RANTES preserves the blood–brain barrier through inhibiting CCR1/SRC/Rac1 pathway after intracerebral hemorrhage in mice

  Yan, J., Xu, W., Lenahan, C., Huang, L., Ocak, U., Wen, J., Li, G., He, W., Le, C., Zhang, J. H., Mo, L. & Tang, J., Dec 2022, In: Fluids and Barriers of the CNS. 19, 1, 7.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Puerarin Attenuates Oxidative Stress and Ferroptosis via AMPK/PGC1α/Nrf2 Pathway after Subarachnoid Hemorrhage in Rats

  Huang, Y., Wu, H., Hu, Y., Zhou, C., Wu, J., Wu, Y., Wang, H., Lenahan, C., Huang, L., Nie, S., Gao, X. & Sun, J., Jul 2022, In: Antioxidants. 11, 7, 1259.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2021

  Activation of Frizzled-7 attenuates blood–brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice

  He, W., Lu, Q., Sherchan, P., Huang, L., Hu, X., Zhang, J. H., Dai, H. & Tang, J., Dec 2021, In: Fluids and Barriers of the CNS. 18, 1, 44.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Activation of Galanin Receptor 1 with M617 Attenuates Neuronal Apoptosis via ERK/GSK-3β/TIP60 Pathway After Subarachnoid Hemorrhage in Rats

  Shi, H., Fang, Y., Huang, L., Gao, L., Lenahan, C., Okada, T., Travis, Z. D., Xie, S., Tang, H., Lu, Q., Liu, R., Tang, J., Cheng, Y. & Zhang, J. H., Jul 2021, In: Neurotherapeutics. 18, 3, p. 1905-1921 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• CCR5 activation promotes NLRP1-dependent neuronal pyroptosis via CCR5/PKA/CREB pathway after intracerebral hemorrhage

  Yan, J., Xu, W., Lenahan, C., Huang, L., Wen, J., Li, G., Hu, X., Zheng, W., Zhang, J. H. & Tang, J., Dec 1 2021, In: Stroke. 52, 12, p. 4021-4032 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• INT-777 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TGR5/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats

  Hu, X., Yan, J., Huang, L., Araujo, C., Peng, J., Gao, L., Liu, S., Tang, J., Zuo, G. & Zhang, J. H., Jan 2021, In: Brain, Behavior, and Immunity. 91, p. 587-600 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Kisspeptin-54 attenuates oxidative stress and neuronal apoptosis in early brain injury after subarachnoid hemorrhage in rats via GPR54/ARRB2/AKT/GSK3β signaling pathway

  Huang, Y., Guo, Y., Huang, L., Fang, Y., Li, D., Liu, R., Lu, Q., Ren, R., Tang, L., Lian, L., Hu, Y., Tang, J., Chen, G. & Zhang, J. H., Aug 1 2021, In: Free Radical Biology and Medicine. 171, p. 99-111 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• LJ529 attenuates mast cell-related inflammation via A₃R-PKCε-ALDH2 pathway after subarachnoid hemorrhage in rats

  Zhang, T., Huang, L., Peng, J., Zhang, J. H. & Zhang, H., Jun 2021, In: Experimental Neurology. 340, 113686.

  Research output: Contribution to journal › Article › peer-review

• Neurokinin Receptor 1 (NK1R) Antagonist Aprepitant Enhances Hematoma Clearance by Regulating Microglial Polarization via PKC/p38MAPK/NFκB Pathway After Experimental Intracerebral Hemorrhage in Mice

  Jin, P., Deng, S., Sherchan, P., Cui, Y., Huang, L., Li, G., Lian, L., Xie, S., Lenahan, C., Travis, Z. D., Zhang, J. H., Gong, Y. & Tang, J., Jul 2021, In: Neurotherapeutics. 18, 3, p. 1922-1938 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Pituitary adenylate cyclase-activating polypeptide attenuates mitochondria-mediated oxidative stress and neuronal apoptosis after subarachnoid hemorrhage in rats

  Fang, Y., Shi, H., Huang, L., Ren, R., Lenahan, C., Xiao, J., Liu, Y., Liu, R., Sanghavi, R., Li, C., Chen, S., Tang, J., Yu, J., Zhang, J. H. & Zhang, J., Oct 2021, In: Free Radical Biology and Medicine. 174, p. 236-248 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice

  Deng, S., Jin, P., Sherchan, P., Liu, S., Cui, Y., Huang, L., Zhang, J. H., Gong, Y. & Tang, J., Dec 2021, In: Journal of Neuroinflammation. 18, 1, 62.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2020

  CCR1 Activation Promotes Neuroinflammation Through CCR1/TPR1/ERK1/2 Signaling Pathway After Intracerebral Hemorrhage in Mice

  Yan, J., Zuo, G., Sherchan, P., Huang, L., Ocak, U., Xu, W., Travis, Z. D., Wang, W., Zhang, J. H. & Tang, J., Jul 1 2020, In: Neurotherapeutics. 17, 3, p. 1170-1183 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Delayed recanalization after MCAO ameliorates ischemic stroke by inhibiting apoptosis via HGF/c-Met/STAT3/Bcl-2 pathway in rats

  Tang, H., Gamdzyk, M., Huang, L., Gao, L., Lenahan, C., Kang, R., Tang, J., Xia, Y. & Zhang, J. H., Aug 2020, In: Experimental Neurology. 330, 113359.

  Research output: Contribution to journal › Article › peer-review

• FSLLRY-NH2 improves neurological outcome after cardiac arrest in rats

  Ocak, U., Ocak, P. E., Huang, L. & Zhang, J. H., 2020, In: Turkish Neurosurgery. 30, 2, p. 244-251 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Inhibition of autophagy signaling via 3-methyladenine rescued nicotine-mediated cardiac pathological effects and heart dysfunctions

  Zhang, P., Li, Y., Fu, Y., Huang, L., Liu, B., Zhang, L., Shao, X. M. & Xiao, D., 2020, In: International Journal of Biological Sciences. 16, 8, p. 1349-1362 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Inhibition of mast cell tryptase attenuates neuroinflammation via PAR-2/p38/NFκB pathway following asphyxial cardiac arrest in rats

  Ocak, U., Eser Ocak, P., Huang, L., Xu, W., Zuo, Y., Li, P., Gamdzyk, M., Zuo, G., Mo, J., Zhang, G. & Zhang, J. H., May 4 2020, In: Journal of Neuroinflammation. 17, 1, 144.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Inhibition of PAR-2 Attenuates Neuroinflammation and Improves Short-Term Neurocognitive Functions Via ERK1/2 Signaling Following Asphyxia-Induced Cardiac Arrest in Rats

  Ocak, U., Ocak, P. E., Huang, L., Zuo, G., Yan, J., Hu, X., Song, Z. & Zhang, J. H., Oct 1 2020, In: Shock. 54, 4, p. 539-547 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• MiRNA-210 induces microglial activation and regulates microglia-mediated neuroinflammation in neonatal hypoxic-ischemic encephalopathy

  Li, B., Dasgupta, C., Huang, L., Meng, X. & Zhang, L., Sep 1 2020, In: Cellular & molecular immunology. 17, 9, p. 976-991 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Noninvasive magnetic resonance imaging stratifies injury severity in a rodent model of male juvenile traumatic brain injury

  Badaut, J., Adami, A., Huang, L. & Obenaus, A., Jan 1 2020, In: Journal of Neuroscience Research. 98, 1, p. 129-140 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Optimizing Radiosurgery for Trigeminal Neuralgia: Impact of Radiation Dose and Anatomic Target on Patient Outcomes

  Wilson, T. A., Karlsson, B., Huang, L., Ramanathan, D., Oyoyo, U. & Boling, W., Nov 2020, In: World Neurosurgery. 143, p. e482-e491

  Research output: Contribution to journal › Article › peer-review

• Pituitary Adenylate Cyclase-Activating Polypeptide Attenuates Brain Edema by Protecting Blood–Brain Barrier and Glymphatic System After Subarachnoid Hemorrhage in Rats

  Fang, Y., Shi, H., Ren, R., Huang, L., Okada, T., Lenahan, C., Gamdzyk, M., Travis, Z. D., Lu, Q., Tang, L., Huang, Y., Zhou, K., Tang, J., Zhang, J. & Zhang, J. H., Oct 2020, In: Neurotherapeutics. 17, 4, p. 1954-1972 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Recombinant CCL17 Enhances Hematoma Resolution and Activation of CCR4/ERK/Nrf2/CD163 Signaling Pathway After Intracerebral Hemorrhage in Mice

  Deng, S., Sherchan, P., Jin, P., Huang, L., Travis, Z., Zhang, J. H., Gong, Y. & Tang, J., Oct 2020, In: Neurotherapeutics. 17, 4, p. 1940-1953 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Rh-CSF1 attenuates neuroinflammation via the CSF1R/PLCG2/PKCϵ pathway in a rat model of neonatal HIE

  Hu, X., Hu, X., Li, S., Li, S., Doycheva, D. M., Huang, L., Huang, L., Lenahan, C., Lenahan, C., Liu, R., Liu, R., Huang, J., Huang, J., Xie, S., Xie, S., Tang, J., Zuo, G., Zuo, G., Zhang, J. H., Zhang, J. H., & 1 othersZhang, J. H., Jun 10 2020, In: Journal of Neuroinflammation. 17, 1, 182.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE

  Hu, X., Li, S., Doycheva, D. M., Huang, L., Lenahan, C., Liu, R., Huang, J., Gao, L., Tang, J., Zuo, G. & Zhang, J. H., 2020, In: Oxidative Medicine and Cellular Longevity. 2020, 6801587.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Stem Cell Therapy in Brain Ischemia: The Role of Mitochondrial Transfer

  Huang, L., Reis, C., Boling, W. W. & Zhang, J. H., May 1 2020, In: Stem Cells and Development. 29, 9, p. 555-561 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The Activation of Phosphatidylserine/CD36/TGF- β 1 Pathway prior to Surgical Brain Injury Attenuates Neuroinflammation in Rats

  Huang, L., Tang, H., Sherchan, P., Lenahan, C., Boling, W., Tang, J. & Zhang, J. H., 2020, In: Oxidative Medicine and Cellular Longevity. 2020, 4921562.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2019

  Abstract WMP79: Phosphatidylserine-containing Liposomes Pretreatment Attenuates Neuroinflammation in a Rat Model of Surgical Brain Injury

  Huang, L., Sherchan, P., Boling, W., Tang, J., Zhang, J. & Zhang, J. H., Feb 1 2019, In: Stroke. 50

  Research output: Contribution to journal › Article › peer-review

• Activation of retinoid X receptor by bexarotene attenuates neuroinflammation via PPARγ/SIRT6/FoxO3a pathway after subarachnoid hemorrhage in rats

  Zuo, Y., Huang, L., Enkhjargal, B., Xu, W., Umut, O., Travis, Z. D., Zhang, G., Tang, J., Liu, F. & Zhang, J. H., Feb 21 2019, In: Journal of Neuroinflammation. 16, 1, 47.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Activation of TGR5 with INT-777 attenuates oxidative stress and neuronal apoptosis via cAMP/PKCε/ALDH2 pathway after subarachnoid hemorrhage in rats

  Zuo, G., Zhang, T., Huang, L., Araujo, C., Peng, J., Travis, Z., Okada, T., Ocak, U., Zhang, G., Tang, J., Lu, X. & Zhang, J. H., Nov 1 2019, In: Free Radical Biology and Medicine. 143, p. 441-453 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A Rat Model of Surgical Brain Injury

  Sherchan, P., McBride, D. W., Huang, L., Reis, C., Akyol, O., Wang, Y., Kim, C., Solaroglu, I., Tang, J., Zhang, J. H. & Zhang, J. H., Jan 1 2019, In: Default journal.

  Research output: Contribution to journal › Article › peer-review

• Foetal hypoxia impacts methylome and transcriptome in developmental programming of heart disease

  Huang, L., Chen, X., Dasgupta, C., Chen, W., Song, R., Wang, C. & Zhang, L., Jul 1 2019, In: Cardiovascular Research. 115, 8, p. 1306-1319 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest

  Huang, L., Applegate, R., Applegate, P., Gong, L., Ocak, U., Boling, W. & Zhang, J., Sep 2019, In: Medical Gas Research. 9, 3, p. 122-126 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Long-term exposure to high altitude hypoxia during pregnancy increases fetal heart susceptibility to ischemia/reperfusion injury and cardiac dysfunction

  Zhang, P., Ke, J., Li, Y., Huang, L., Chen, Z., Huang, X., Zhang, L. & Xiao, D., Jan 1 2019, In: International Journal of Cardiology. 274, p. 7-15 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• LRP1 activation attenuates white matter injury by modulating microglial polarization through Shc1/PI3K/Akt pathway after subarachnoid hemorrhage in rats

  Peng, J., Pang, J., Huang, L., Enkhjargal, B., Zhang, T., Mo, J., Wu, P., Xu, W., Zuo, Y., Peng, J., Zuo, G., Chen, L., Tang, J., Zhang, J. H. & Jiang, Y., Feb 2019, In: Redox Biology. 21, 101121.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• MicroRNA-210 Downregulates ISCU and Induces Mitochondrial Dysfunction and Neuronal Death in Neonatal Hypoxic-Ischemic Brain Injury

  Ma, Q., Dasgupta, C., Li, Y., Huang, L. & Zhang, L., Aug 15 2019, In: Molecular Neurobiology. 56, 8, p. 5608-5625 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Multi-omics integration reveals short and long-term effects of gestational hypoxia on the heart development

  Gao, Y., Dasgupta, C., Huang, L., Song, R., Zhang, Z. & Zhang, L., Dec 2019, In: Cells. 8, 12, 1608.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• RO27-3225 attenuates NLRP1-dependent neuronal pyroptosis via MC4R/ASK1/JNK/p38 MAPK pathway in a mouse model of intracerebral hemorrhage

  Chen, S., Chen, S., Zuo, Y., Zuo, Y., Huang, L., Huang, L., Sherchan, P., Zhang, J., Yu, Z., Peng, J., Zhang, J., Zhao, L., Doycheva, D., Liu, F., Zhang, J. H., Zhang, J. H., Xia, Y. & Tang, J., Feb 27 2019, In: British Journal of Pharmacology.

  Research output: Contribution to journal › Article › peer-review

• Secukinumab attenuates reactive astrogliosis via IL-17RA/(C/EBPβ)/SIRT1 pathway in a rat model of germinal matrix hemorrhage

  Liu, S. P., Huang, L., Flores, J., Ding, Y., Li, P., Peng, J., Zuo, G., Zhang, J. H., Lu, J. & Tang, J. P., Oct 1 2019, In: CNS Neuroscience and Therapeutics. 25, 10, p. 1151-1161 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access