Regenerative Medicine Division

Research output

Research output per year 1963 1977 1979 1982 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2005 2006 2007 2013 2024

• 636 Article
• 37 Other contribution
• 26 Review article
• 10 Chapter
• 28 More
  • 8 Letter
  • 6 Comment/debate
  • 5 Editorial
  • 3 Digital or Visual Products
  • 2 Conference contribution
  • 2 Paper
  • 1 Poster
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2024

  Enhancing Human Treg Cell Induction through Engineered Dendritic Cells and Zinc Supplementation

  Shaikh, N. A., Zhang, X. B., Abdalla, M. I., Baylink, D. J. & Tang, X., 2024, In: Critical Reviews in Immunology. 44, 3, p. 37-52 16 p.

  Research output: Contribution to journal › Article › peer-review
• 2023

  Transient TKI-resistant CD44+pBAD+ blasts undergo intrinsic homeostatic adaptation to promote the survival of acute myeloid leukemia in vitro

  Xu, Y., Baylink, D. J., Chen, C. S., Tan, L., Xiao, J., Park, B., Valladares, I., Reeves, M. E. & Cao, H., 2023, In: Frontiers in Oncology. 13, 1286863.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2022

  Calcium released by osteoclastic resorption stimulates autocrine/paracrine activities in local osteogenic cells to promote coupled bone formation

  Ahmed, A. S. I., Sheng, M. H. C., Lau, K. H. W., Wilson, S. M., Wongwarawat, D., Tang, X., Ghahramanpouri, M., Nehme, A., Xu, Y., Abdipour, A., Zhang, X. B., Wasnik, S. & Baylink, D. J., May 2022, In: American Journal of Physiology - Cell Physiology. 322, 5, p. C977-C990

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Combination therapy of insulin-like growth factor I and BTP-2 markedly improves lipopolysaccharide-induced liver injury in mice

  Nehme, A., Ghahramanpouri, M., Ahmed, I., Golsorkhi, M., Thomas, N., Munoz, K., Abdipour, A., Tang, X., Wilson, S. M., Wasnik, S. & Baylink, D. J., Aug 2022, In: FASEB Journal. 36, 8, e22444.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Defective bone repletion in aged Balb/cBy mice was caused by impaired osteoblastic differentiation

  Sheng, M. H. C., Lau, K. H. W., Rundle, C. H., Alsunna, A., Wilson, S. M. & Baylink, D. J., Nov 2022, In: Journal of Bone and Mineral Metabolism. 40, 6, p. 900-913 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• FBP1-Altered Carbohydrate Metabolism Reduces Leukemic Viability through Activating P53 and Modulating the Mitochondrial Quality Control System In Vitro

  Xu, Y., Tran, L., Tang, J., Nguyen, V., Sewell, E., Xiao, J., Hino, C., Wasnik, S., Francis-Boyle, O. L., Zhang, K. K., Xie, L., Zhong, J. F., Baylink, D. J., Chen, C. S., Reeves, M. E. & Cao, H., Oct 2022, In: International Journal of Molecular Sciences. 23, 19, 11387.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeting TKI-Activated NFKB2-MIF/CXCLs-CXCR2 Signaling Pathways in FLT3 Mutated Acute Myeloid Leukemia Reduced Blast Viability

  Cao, H., Tadros, V., Hiramoto, B., Leeper, K., Hino, C., Xiao, J., Pham, B., Kim, D. H., Reeves, M. E., Chen, C. S., Zhong, J. F., Zhang, K. K., Xie, L., Wasnik, S., Baylink, D. J. & Xu, Y., May 2022, In: Biomedicines. 10, 5, 1038.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2021

  Ex vivo isolation, expansion and bioengineering of CCR7+CD95-/or CD62L+CD45RA+ tumor infiltrating lymphocytes from acute myeloid leukemia patients’ bone marrow

  Cao, H., Kim, D. H., Howard, A., Moz, H., Wasnik, S., Baylink, D. J., Chen, C. S., Reeves, M. E., Mirshahidi, S., Xiao, J., Francis, O., Marcucci, G. & Xu, Y., Dec 2021, In: Neoplasia (United States). 23, 12, p. 1252-1260 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• HDAC inhibitors improve CRISPR-mediated HDR editing efficiency in iPSCs

  Zhang, J. P., Yang, Z. X., Zhang, F., Fu, Y. W., Dai, X. Y., Wen, W., Zhang, B., Choi, H., Chen, W., Brown, M., Baylink, D., Zhang, L., Qiu, H., Wang, C., Cheng, T. & Zhang, X. B., Sep 2021, In: Science China Life Sciences. 64, 9, p. 1449-1462 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Inflammation-and gut-homing macrophages, engineered to de novo overexpress active vitamin d, promoted the regenerative function of intestinal stem cells

  Xu, Y., Baylink, D. J., Cao, H., Xiao, J., Abdalla, M. I., Wasnik, S. & Tang, X., Sep 1 2021, In: International Journal of Molecular Sciences. 22, 17, 9516.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The effects of insulin-like growth factor i and btp-2 on acute lung injury

  Munoz, K., Wasnik, S., Abdipour, A., Bi, H., Wilson, S. M., Tang, X., Ghahramanpouri, M. & Baylink, D. J., May 2 2021, In: International Journal of Molecular Sciences. 22, 10, 5244.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2020

  A novel vitamin D gene therapy for acute myeloid leukemia

  Xu, Y., Payne, K., Pham, L. H. G., Eunwoo, P., Xiao, J., Chi, D., Lyu, J., Campion, R., Wasnik, S., Jeong, I. S., Tang, X., Baylink, D. J., Chen, C. S., Reeves, M., Akhtari, M., Mirshahidi, S., Marcucci, G. & Cao, H., Dec 2020, In: Translational Oncology. 13, 12, 100869.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Discovery of proangiogenic CD44+mesenchymal cancer stem cells in an acute myeloid leukemia patient's bone marrow

  Cao, H., Xiao, J., Reeves, M. E., Payne, K., Chen, C. S., Baylink, D. J., Marcucci, G., Xu, Y. & Xu, Y., Jun 3 2020, In: Journal of Hematology and Oncology. 13, 1, 63.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Fluoride Therapy for the Vertebral Crush Fracture Syndrome

  Heaney, R. P., Baylink, D. J., Johnston, C. C., Melton, L. J., Meunier, P. J., Murray, T. M. & de Deuxchaisnes, C. N., Mar 10 2020, In: Annals of Internal Medicine.

  Research output: Contribution to journal › Article › peer-review

• IGF-1 deficiency rescue and intracellular calcium blockade improves survival and corresponding mechanisms in a mouse model of acute kidney injury

  Wasnik, S., Tang, X., Bi, H., Abdipour, A., Carreon, E. E., Sutjiadi, B., Lyu, J., Zhang, J., Wilson, S. & Baylink, D. J., Jun 1 2020, In: International Journal of Molecular Sciences. 21, 11, p. 1-17 17 p., 4095.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Unique anabolic action of stem cell gene therapy overexpressing PDGFB-DSS6 fusion protein in OVX osteoporosis mouse model

  Chen, W., Wasnik, S., Fu, Y., Aranda, L., Rundle, C. H., Lau, K. H. W., Baylink, D. J. & Zhang, X., Jun 2020, In: Bone Reports. 12, 100236.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2019

  Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90⁺ skeletal stem cells in fracture sites

  Wasnik, S., Lakhan, R., Baylink, D. J., Rundle, C. H., Xu, Y., Zhang, J., Qin, X., Lau, K. H. W., Carreon, E. E. & Tang, X., Jul 31 2019, In: Science Advances. 5, 7, eaaw2108.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• In vivo augmentation of gut-homing regulatory T cell induction

  Bi, H., Wasnik, S., Baylink, D. J., Liu, C. & Tang, X., Jan 2019, In: Journal of Visualized Experiments. 2020, 155, e60585.

  Research output: Contribution to journal › Article › peer-review

• In vivo generation of gut-homing regulatory T cells for the suppression of colitis

  Xu, Y., Cheng, Y., Baylink, D. J., Wasnik, S., Goel, G., Huang, M., Cao, H., Qin, X., Lau, K. H. W., Chan, C., Koch, A., Pham, L. H., Zhang, J., Li, C. H., Wang, X., Berumen, E. C., Smith, J. & Tang, X., Jun 15 2019, In: Journal of Immunology. 202, 12, p. 3447-3457 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Mechanistic study of the cause of decreased blood 1,25-Dihydroxyvitamin D in sepsis

  Li, C. H., Tang, X., Wasnik, S., Wang, X., Zhang, J., Xu, Y., Lau, K. H. W., Nguyen, H. B. & Baylink, D. J., Dec 2 2019, In: BMC Infectious Diseases. 19, 1, 1020.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2018

  1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites

  Wasnik, S., Rundle, C. H., Baylink, D. J., Yazdi, M. S., Carreon, E. E., Xu, Y., Qin, X., Lau, K. H. W. & Tang, X., Sep 6 2018, In: JCI insight. 3, 17

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Deficient arginase II expression without alteration in arginase I expression attenuated experimental autoimmune encephalomyelitis in mice

  Choudry, M., Tang, X., Santorian, T., Wasnik, S., Xiao, J., Xing, W., Lau, K. H. W., Mohan, S., Baylink, D. J. & Qin, X., Sep 2018, In: Immunology. 155, 1, p. 85-98 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Detection of dinitrosyl iron complexes by ozone-based chemiluminescence

  Mukosera, G. T., Liu, T., Ishtiaq Ahmed, A. S., Li, Q., Sheng, M. H. C., Tipple, T. E., Baylink, D. J., Power, G. G. & Blood, A. B., Sep 1 2018, In: Nitric Oxide - Biology and Chemistry. 79, p. 57-67 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Effect of Residual Dental Pulp Tissue on Regeneration of Dentin-pulp Complex: An In Vivo Investigation

  Torabinejad, M., Alexander, A., Vahdati, S. A., Grandhi, A., Baylink, D. & Shabahang, S., Dec 2018, In: Journal of Endodontics. 44, 12, p. 1796-1801 6 p.

  Research output: Contribution to journal › Article › peer-review

• Highly efficient genome editing via CRISPR–Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression

  Li, X. L., Li, G. H., Fu, J., Fu, Y. W., Zhang, L., Chen, W., Arakaki, C., Zhang, J. P., Wen, W., Zhao, M., Chen, W. V., Botimer, G. D., Baylink, D., Aranda, L., Choi, H., Bechar, R., Talbot, P., Sun, C. K., Cheng, T. & Zhang, X. B., Nov 2 2018, In: Nucleic Acids Research. 46, 19, p. 10195-10215 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2017

  Dendritic cells, engineered to overexpress 25-hydroxyvitamin D 1α-hydroxylase and pulsed with a myelin antigen, provide myelin-specific suppression of ongoing experimental allergic encephalomyelitis

  Li, C. H., Zhang, J., Baylink, D. J., Wang, X., Goparaju, N. B., Xu, Y., Wasnik, S., Cheng, Y., Berumen, E. C., Qin, X., Lau, K. H. W. & Tang, X., Jul 2017, In: FASEB Journal. 31, 7, p. 2996-3006 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Effect of aging on stem cells.

  Sheng, M. H., Wasnik, S., Baylink, D. J., Lau, K-H. W. & Lau, K-H. W., Feb 20 2017, In: World Journal of Experimental Medicine. 7

  Research output: Contribution to journal › Article › peer-review

• Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage

  Zhang, J. P., Li, X. L., Li, G. H., Chen, W., Arakaki, C., Botimer, G. D., Baylink, D., Zhang, L., Wen, W., Fu, Y. W., Xu, J., Chun, N., Yuan, W., Cheng, T. & Zhang, X. B., Feb 20 2017, In: Genome Biology. 18, 1, 35.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Generation of integration-free induced pluripotent stem cells from human peripheral blood mononuclear cells using episomal vectors

  Wen, W., Zhang, J. P., Chen, W., Arakaki, C., Li, X., Baylink, D., Botimer, G. D., Xu, J., Yuan, W., Cheng, T. & Zhang, X. B., Jan 1 2017, In: Journal of Visualized Experiments. 2017, 119, e55091.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• HSC Niche: Regulation of Mobilization and Homing

  Wasnik, S., Chen, W., Zhang, X-B., Tang, X. & Baylink, D. J., Jan 1 2017, In: Biology and Engineering of Stem Cell Niches.

  Research output: Contribution to journal › Article › peer-review

• Overlapping peptide library to map Qa-1 epitopes in a protein

  Xu, Y., Wasnik, S., Baylink, D. J., Berumen, E. C. & Tang, X., Dec 20 2017, In: Journal of Visualized Experiments. 2017, 130, e56401.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Unique regenerative mechanism to replace bone lost during dietary bone depletion in weanling mice

  Sheng, M. H. C., William Lau, K. H., Lakhan, R., Ahmed, A. S. I., Rundle, C. H., Biswanath, P. & Baylink, D. J., Apr 1 2017, In: Endocrinology. 158, 4, p. 714-729 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2016

  A METHOD FOR UTILIZING ENGINEERED DENDRITIC CELLS TO INDUCE GUT-HOMING REGULATORY T CELLS AND TREAT GUT INFLAMMATION

  Tang, X., Baylink, D. J., Lau, H. W. K. & Walter, M., Feb 11 2016, In: Default journal.

  Research output: Contribution to journal › Article › peer-review

• A Novel Calcitriol-producing, Gut-homing CD11b+Gr-1+ Macrophage Specifically Homes to the Inflamed Gut and Robustly Suppresses an Immune-mediated Experimental Colitis: 706

  Xu, Y., Cheng, Y., Cao, H., Baylink, D., Goel, G. & Tang, X., Oct 1 2016, In: The American Journal of Gastroenterology. 111

  Research output: Contribution to journal › Article › peer-review

• Conditional deletion of IGF-I in osteocytes unexpectedly accelerates bony union of the fracture gap in mice

  Lau, K. H. W., Rundle, C. H., Zhou, X. D., Baylink, D. J. & Sheng, M. H. C., Nov 1 2016, In: Bone. 92, p. 18-28 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• MicroRNA223 promotes pathogenic T-cell development and autoimmune inflammation in central nervous system in mice

  Satoorian, T., Li, B., Tang, X., Xiao, J., Xing, W., Shi, W., Lau, K. H. W., Baylink, D. J. & Qin, X., Aug 1 2016, In: Immunology. 148, 4, p. 326-338 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeting non-classical myelin epitopes to treat experimental autoimmune encephalomyelitis

  Wang, X., Zhang, J., Baylink, D. J., Li, C. H., Watts, D. M., Xu, Y., Qin, X., Walter, M. H. & Tang, X., Oct 31 2016, In: Scientific Reports. 6, 36064.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Vitamin D status and metabolism in an ovine pregnancy model: Effect of long-term, high-altitude hypoxia

  Goyal, R., Billings, T. L., Mansour, T., Martin, C., Baylink, D. J., Longo, L. D., Pearce, W. J. & Mata-Greenwood, E., Jun 1 2016, In: American Journal of Physiology - Endocrinology and Metabolism. 310, 11, p. E1062-E1071

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2015

  Local administration of AAV-DJ pseudoserotype expressing COX2 provided early onset of transgene expression and promoted bone fracture healing in mice

  Lakhan, R., Baylink, D. J., Lau, K. H. W., Tang, X., Sheng, M. H. C., Rundle, C. H. & Qin, X., Sep 5 2015, In: Gene Therapy. 22, 9, p. 721-728 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Osteocyte-derived insulin-like growth factor I is not essential for the bone repletion response in mice

  Lau, K. H. W., Baylink, D. J. & Sheng, M. H. C., Jan 30 2015, In: PLoS ONE. 10, 1, e0115897.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Patient-specific cardiovascular progenitor cells derived from integration-free induced pluripotent stem cells for vascular tissue regeneration

  Hu, J., Wang, Y., Jiao, J., Liu, Z., Zhao, C., Zhou, Z., Zhang, Z., Forde, K., Wang, L., Wang, J., Baylink, D. J., Zhang, X. B., Gao, S., Yang, B., Chen, Y. E. & Ma, P. X., Dec 2015, In: Biomaterials. 73, p. 51-59 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• PDGFB-based stem cell gene therapy increases bone strength in the mouse

  Chen, W., Baylink, D. J., Brier-Jones, J., Neises, A., Kiroyan, J. B., Rundle, C. H., Lau, K. H. W. & Zhang, X. B., Jul 21 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 29, p. E3893-E3900

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeted 25-hydroxyvitamin D₃ 1α-hydroxylase adoptive gene therapy ameliorates DSS-induced colitis without causing hypercalcemia in mice

  Li, B., Baylink, D. J., Walter, M. H., Lau, K. H. W., Meng, X., Wang, J., Cherkas, A., Tang, X. & Qin, X., Feb 3 2015, In: Molecular Therapy. 23, 2, p. 339-351 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2014

  Characterization of an animal model of pregnancy-induced vitamin D deficiency due to metabolic gene dysregulation

  Goyal, R., Zhang, L., Blood, A. B., Baylink, D. J., Longo, L. D., Oshiro, B. & Mata-Greenwood, E., Feb 1 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 306, 3, p. E256-E266

  Research output: Contribution to journal › Article › peer-review

• Maternal infection with Schistosoma japonicum induces a profibrotic response in neonates

  McDonald, E. A., Cheng, L., Jarilla, B., Sagliba, M. J., Gonzal, A., Amoylen, A. J., Olveda, R., Acosta, L., Baylink, D., White, E. S., Friedman, J. F. & Kurtis, J. D., Jan 2014, In: Infection and Immunity. 82, 1, p. 350-355 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone

  Sheng, M. H. C., Lau, K. H. W. & Baylink, D. J., Feb 1 2014, In: Journal of Bone Metabolism. 21

  Research output: Contribution to journal › Article › peer-review
• 2013

  1,25-Dihydroxyvitamin D3 Suppresses TLR8 Expression and TLR8-Mediated Inflammatory Responses in Monocytes In Vitro and Experimental Autoimmune Encephalomyelitis In Vivo

  Li, B., Baylink, D. J., Deb, C., Zannetti, C., Rajaallah, F., Xing, W., Walter, M. H., Lau, K. H. W. & Qin, X., Mar 14 2013, In: PLoS ONE. 8, 3, e58808.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Cellular and molecular mechanisms of accelerated fracture healing by COX2 gene therapy. Studies in a mouse model of multiple fractures.

  Lau, K. H. W., Kothari, V., Das, A., Zhang, X. B. & Baylink, D. J., Apr 2013, In: Bone. 53, 2, p. 369-381 13 p.

  Research output: Contribution to journal › Article › peer-review

• Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice

  Sheng, M. H. C., Zhou, X. D., Bonewald, L. F., Baylink, D. J. & Lau, K. H. W., Jan 2013, In: Bone. 52, 1, p. 133-144 12 p.

  Research output: Contribution to journal › Article › peer-review

• Efficient Generation of Integration-Free iPS Cells from Human Adult Peripheral Blood Using BCL-XL Together with Yamanaka Factors

  Su, R. J., Baylink, D. J., Neises, A., Kiroyan, J. B., Meng, X., Payne, K. J., Tschudy-Seney, B., Duan, Y., Appleby, N., Kearns-Jonker, M., Gridley, D. S., Wang, J., Lau, K. H. W. & Zhang, X. B., May 21 2013, In: PLoS ONE. 8, 5, e64496.

  Research output: Contribution to journal › Article › peer-review

  Open Access